Tetrahydrofuran → N-[2-{4-[1-(4-fluorophenylmethyl)-1H-benzimidazol-2-ylamino]-1-piperidinyl}ethyl]-N'-(2-nitrophenyl)thiourea
Reaction equation
[N:1](=[C:2]=[S:3])[c:4]1[c:5]([N+:10](=[O:11])[O-:12])[cH:6][cH:7][cH:8][cH:9]1.[NH2:13][CH2:14][CH2:15][N:16]1[CH2:17][CH2:18][CH:19]([NH:22][c:23]2[n:24][c:25]3[c:26]([n:27]2[CH2:28][c:29]2[cH:30][cH:31][c:32]([F:35])[cH:33][cH:34]2)[cH:36][cH:37][cH:38][cH:39]3)[CH2:20][CH2:21]1.[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[NH:1]([C:2](=[S:3])[NH:13][CH2:14][CH2:15][N:16]1[CH2:17][CH2:18][CH:19]([NH:22][c:23]2[n:24][c:25]3[c:26]([n:27]2[CH2:28][c:29]2[cH:30][cH:31][c:32]([F:35])[cH:33][cH:34]2)[cH:36][cH:37][cH:38][cH:39]3)[CH2:20][CH2:21]1)[c:4]1[c:5]([N+:10](=[O:11])[O-:12])[cH:6][cH:7][cH:8][cH:9]1Participants
4
Sources & evidence
- ORD record
- ord-669e2727eded4911954f92cadedb791e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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