Pyridine → [1-[[5-Tert-butyl-2-(5-chloro-2-methoxybenzoyl)imino-1,3-thiazol-3-yl]methyl]cyclobutyl] acetate

HRID 952034Notes

Reaction equation

HRID 952034 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][n:7]([CH2:22][C:23]2([OH:27])[CH2:24][CH2:25][CH2:26]2)[c:8](=[N:10][C:11]([c:12]2[c:13]([O:19][CH3:20])[cH:14][cH:15][c:16]([Cl:18])[cH:17]2)=[O:21])[s:9]1.[CH3:28][C:29](=[O:30])[O:31][C:32](=[O:33])[CH3:34].[CH3:35][N:36]([CH3:37])[c:38]1[cH:39][cH:40][n:41][cH:42][cH:43]1.[cH:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][n:7]([CH2:22][C:23]2([O:27][C:29]([CH3:28])=[O:30])[CH2:24][CH2:25][CH2:26]2)[c:8](=[N:10][C:11]([c:12]2[c:13]([O:19][CH3:20])[cH:14][cH:15][c:16]([Cl:18])[cH:17]2)=[O:21])[s:9]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 7918Acetic AnhydrideHCID 142844-(Dimethylamino)pyridineHCID 66851876N-[5-tert-butyl-3-[(1-hydroxycyclobutyl)methyl]-1,3-thiazol-2-ylidene]-5-chloro-2-methoxybenzamide

Product 1

HCID 66851500[1-[[5-Tert-butyl-2-(5-chloro-2-methoxybenzoyl)imino-1,3-thiazol-3-yl]methyl]cyclobutyl] acetate

Sources & evidence

ORD record
ord-ec16a55de2344a099330b4673385424e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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