Hydrochloric Acid → 2-(3-Methylisonicotinamido)-5-(3-(trifluoromethyl)phenyl)thiazole-4-carboxylic acid
Reaction equation
[CH3:2][c:3]1[c:4]([C:5](=[O:6])[NH:7][c:8]2[s:9][c:10](-[c:17]3[cH:18][c:19]([C:23]([F:24])([F:25])[F:26])[cH:20][cH:21][cH:22]3)[c:11]([C:13](=[O:14])[O:15][CH3:16])[n:12]2)[cH:27][cH:28][n:29][cH:30]1.[ClH:1].[F:31][c:32]1[cH:33][cH:34][cH:35][c:36]([F:37])[c:38]1[C:39]([NH:40][c:41]1[s:42][c:43](-[c:44]2[cH:45][cH:46][cH:47][c:48]([C:49]([F:50])([F:51])[F:52])[cH:53]2)[c:54]([C:55]([OH:56])=[O:57])[n:58]1)=[O:59]>>[CH3:2][c:3]1[c:4]([C:5](=[O:6])[NH:7][c:8]2[s:9][c:10](-[c:17]3[cH:18][c:19]([C:23]([F:24])([F:25])[F:26])[cH:20][cH:21][cH:22]3)[c:11]([C:13](=[O:14])[OH:15])[n:12]2)[cH:27][cH:28][n:29][cH:30]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-54187614abaa4a79bd06c98a7b30f0b4
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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