2-Aminothiazole → 3-cyclohexyl-2-(5,6-dichloro-3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)propanamide
Reaction equation
[CH:1]1([CH2:7][CH:8]([C:9](=[O:10])[OH:11])[N:12]2[C:13](=[O:23])[c:14]3[cH:15][c:16]([Cl:22])[c:17]([Cl:21])[cH:18][c:19]3[CH2:20]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:30]1([CH2:31][CH:32]([N:33]2[CH2:34][c:35]3[c:36]([cH:37][cH:38][cH:39][cH:40]3)[C:41]2=[O:42])[C:43]([NH:44][c:45]2[s:46][cH:47][cH:48][n:49]2)=[O:50])[CH2:51][CH2:52][CH2:53][CH2:54][CH2:55]1.[NH2:24][c:25]1[s:26][cH:27][cH:28][n:29]1>>[CH:1]1([CH2:7][CH:8]([C:9](=[O:10])[NH:24][c:25]2[s:26][cH:27][cH:28][n:29]2)[N:12]2[C:13](=[O:23])[c:14]3[cH:15][c:16]([Cl:22])[c:17]([Cl:21])[cH:18][c:19]3[CH2:20]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-696cd436b2884b96a52b40030fe79251
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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