Sodium ion → 2-Benzyl-1-(1-methoxy-1-methylethyl)-1,2,3,4-tetrahydroisoquinoline

HRID 952256Notes

Reaction equation

HRID 952256 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH:9]([C:18]([CH3:19])([CH3:20])[OH:21])[c:10]2[cH:11][cH:12][cH:13][cH:14][c:15]2[CH2:16][CH2:17]1.[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:24][I:25].[H-:22].[Na+:23].[OH2:26]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH:9]([C:18]([CH3:19])([CH3:20])[O:21][CH3:24])[c:10]2[cH:11][cH:12][cH:13][cH:14][c:15]2[CH2:16][CH2:17]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 166653HydrideHCID 59396310HCID 59396310, compound

Product 1

HCID 593964802-Benzyl-1-(1-methoxy-1-methylethyl)-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-4ee060e73f224c26827c4e80f793daf3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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