Tetrahydrofuran → racemic 2,2,2-trifluoro-N-(3-hydroxy-6-methyl-2,3-dihydro-1H-inden-1-yl)acetamide
Reaction equation
[CH2:1]([O:2][CH:3]1[c:4]2[c:5]([cH:6][c:7]([O:8][CH2:9][CH2:10][CH3:11])[cH:12][cH:13]2)[CH:14]([NH2:15])[CH2:16]1)[CH:17]=[CH2:18].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[F:19][C:20]([C:21](=[O:22])[NH:23][CH:24]1[CH2:25][C:26](=[O:34])[c:27]2[cH:28][cH:29][c:30]([CH3:33])[cH:31][c:32]21)([F:35])[F:36]>>[F:19][C:20]([C:21](=[O:22])[NH:23][CH:24]1[CH2:25][CH:26]([OH:34])[c:27]2[cH:28][cH:29][c:30]([CH3:33])[cH:31][c:32]21)([F:35])[F:36]Participants
4
Sources & evidence
- ORD record
- ord-eea9ff2511294b3b83cd20716e42f97e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…