Imidazole → Cyclopentanol, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

HRID 952363Notes

Reaction equation

HRID 952363 reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[Si:17]([CH3:18])([CH3:19])[Cl:20].[CH:1]1([OH:7])[CH2:2][CH:3]([OH:6])[CH2:4][CH2:5]1.[O:22]=[CH:23][N:24]([CH3:25])[CH3:26].[OH2:21].[nH:8]1[cH:9][cH:10][n:11][cH:12]1>>[CH:1]1([OH:7])[CH2:2][CH:3]([O:6][Si:17]([C:13]([CH3:14])([CH3:15])[CH3:16])([CH3:18])[CH3:19])[CH2:4][CH2:5]1

Participants

6

Reactant 5

HCID 795ImidazoleHCID 962WaterHCID 6228DimethylformamideHCID 28928tert-Butyldimethylsilyl chlorideHCID 100165Cyclopentane-1,3-diol

Product 1

HCID 21938628Cyclopentanol, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

Sources & evidence

ORD record
ord-3f28da42a0d6454ab85a69edce89d688
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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