Morpholine → 8-(1-(3,5-difluorophenyl)pyrrolidin-2-yl)-6-(morpholine-4-carbonyl)-2-morpholino-4H-chromen-4-one
Reaction equation
[CH2:43]1[CH2:44][O:45][CH2:46][CH2:47][NH:48]1.[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[F:1][c:2]1[cH:3][c:4]([N:9]2[CH:10]([c:14]3[cH:15][c:16]([C:31](=[O:32])[OH:33])[cH:17][c:18]4[c:19](=[O:30])[cH:20][c:21]([N:24]5[CH2:25][CH2:26][O:27][CH2:28][CH2:29]5)[o:22][c:23]34)[CH2:11][CH2:12][CH2:13]2)[cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[cH:3][c:4]([N:9]2[CH:10]([c:14]3[cH:15][c:16]([C:31](=[O:33])[N:48]4[CH2:43][CH2:44][O:45][CH2:46][CH2:47]4)[cH:17][c:18]4[c:19](=[O:30])[cH:20][c:21]([N:24]5[CH2:25][CH2:26][O:27][CH2:28][CH2:29]5)[o:22][c:23]34)[CH2:11][CH2:12][CH2:13]2)[cH:5][c:6]([F:8])[cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-84b8f51945b54122aed349e01cb9bde6
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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