Diethyl Ether → 1-(2,2,3,3-Tetrafluorobenzofuran-5-yl)-2,2,2-trifluoroethanone

HRID 952717Notes

Reaction equation

HRID 952717 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:14]1)[C:7]([F:12])([F:13])[C:8]([F:10])([F:11])[O:9]2.[CH3:16][O:17][N:18]([C:19]([C:20]([F:21])([F:22])[F:23])=[O:24])[CH3:25].[CH3:26][CH2:27][O:28][CH2:29][CH3:30].[Mg:15]>>[c:2]1([C:19]([C:20]([F:21])([F:22])[F:23])=[O:24])[cH:3][cH:4][c:5]2[c:6]([cH:14]1)[C:7]([F:12])([F:13])[C:8]([F:10])([F:11])[O:9]2

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 27823822,2,2-Trifluoro-N-methoxy-N-methylacetamideHCID 5462224MagnesiumHCID 142984965-Bromo-2,2,3,3-tetrafluorobenzofuran

Product 1

HCID 146269631-(2,2,3,3-Tetrafluorobenzofuran-5-yl)-2,2,2-trifluoroethanone

Sources & evidence

ORD record
ord-a1ae43e0d8df4664bac869cd88ae7288
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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