Acetic Acid → 6-(4-chloro-1H-imidazol-1-yl)-5-methoxypyridin-3-amine

HRID 952749Notes

Reaction equation

HRID 952749 reaction equation
[CH3:18][CH2:19][OH:20].[CH3:24][C:25](=[O:26])[OH:27].[Cl:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[n:8][cH:9][c:10]([N+:15]([O-:16])=[O:17])[cH:11][c:12]2[O:13][CH3:14])[cH:6]1.[Fe:23].[Na+:22].[OH-:21]>>[Cl:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[n:8][cH:9][c:10]([NH2:15])[cH:11][c:12]2[O:13][CH3:14])[cH:6]1

Participants

7

Reactant 6

HCID 176Acetic AcidHCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 23925IronHCID 580753262-(4-chloro-1H-imidazol-1-yl)-3-methoxy-5-nitropyridine

Product 1

HCID 580754656-(4-chloro-1H-imidazol-1-yl)-5-methoxypyridin-3-amine

Sources & evidence

ORD record
ord-c6499a42d48e4bafbb69869c213c48f2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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