Methanol → Tert-butyl (piperidin-4-ylmethyl)carbamate

HRID 952776Notes

Reaction equation

HRID 952776 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[N:11]1[CH2:12][CH2:13][CH:14]([CH2:17][NH:18][C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:15][CH2:16]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:33][OH:34].[H:31][H:32]>>[NH:11]1[CH2:12][CH2:13][CH:14]([CH2:17][NH:18][C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:15][CH2:16]1

Participants

5

Reactant 4

HCID 887MethanolHCID 8028TetrahydrofuranHCID 23577280Benzyl 4-{[(tert-butoxycarbonyl)amino]methyl}piperidine-1-carboxylateHCID 178418361HCID 178418361, compound

Product 1

HCID 723429Tert-butyl (piperidin-4-ylmethyl)carbamate

Sources & evidence

ORD record
ord-bf5690285a8944719a892e05cd332a8f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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