Dichloromethane → 4-(4-Chlorophenyl)-4-methoxy-3-methyl-3-piperidinol

HRID 952849Notes

Reaction equation

HRID 952849 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][C:10]([CH3:23])([OH:24])[C:11]([O:14][CH3:15])([c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:32]([Cl:33])[Cl:34].[OH:25][C:26]([C:27]([F:28])([F:29])[F:30])=[O:31]>>[NH:8]1[CH2:9][C:10]([CH3:23])([OH:24])[C:11]([O:14][CH3:15])([c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 66757870HCID 66757870, compound

Product 1

HCID 231368654-(4-Chlorophenyl)-4-methoxy-3-methyl-3-piperidinol

Sources & evidence

ORD record
ord-282ae361eec74f7b9de2bc2dcba44b7c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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