Isopropanol → N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-5-(3-chloropropyl)-5H-pyrrolo[3,2-d]pyrimidin-4-amine
Reaction equation
[CH:32]([OH:33])([CH3:34])[CH3:35].[Cl:15][c:16]1[cH:17][c:18]([NH2:19])[cH:20][cH:21][c:22]1[O:23][CH2:24][c:25]1[cH:26][c:27]([F:31])[cH:28][cH:29][cH:30]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][n:10]2[CH2:11][CH2:12][CH2:13][Cl:14]>>[c:2]1([NH:19][c:18]2[cH:17][c:16]([Cl:15])[c:22]([O:23][CH2:24][c:25]3[cH:26][c:27]([F:31])[cH:28][cH:29][cH:30]3)[cH:21][cH:20]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][n:10]2[CH2:11][CH2:12][CH2:13][Cl:14]Participants
4
Sources & evidence
- ORD record
- ord-49d47c3ec61949e2a51207a070eba196
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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