Acetic Acid → 5-Bromo-3-cyanoindole

HRID 952876Notes

Reaction equation

HRID 952876 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([CH:11]=[O:12])[cH:6][nH:7][c:8]2[cH:9][cH:10]1.[CH3:26][C:27](=[O:28])[OH:29].[N+:20]([CH2:21][CH2:22][CH3:23])([O-:24])=[O:25].[NH4+:13].[NH4+:14].[OH:15][P:16](=[O:17])([O-:18])[O-:19]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([C:11]#[N:13])[cH:6][nH:7][c:8]2[cH:9][cH:10]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 223Ammonium2×HCID 79031-NitropropaneHCID 701375-Bromoindole-3-carbaldehydeHCID 3681305Hydrogen phosphate

Product 1

HCID 36233545-Bromo-3-cyanoindole

Sources & evidence

ORD record
ord-8a58ea1902794255872f7d0270a43aac
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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