Potassium Cation → 2-{2-Chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-6-methoxy-4-(methoxycarbonyl)methoxypyrimidine

HRID 952990Notes

Reaction equation

HRID 952990 reaction equation
[C:46](=[O:47])([O-:48])[O-:49].[CH3:23][O:24][c:25]1[cH:26][c:27]([O:35][CH2:36][C:37](=[O:38])[O:39][CH3:40])[n:28][c:29]([S:31]([CH3:32])(=[O:33])=[O:34])[n:30]1.[CH3:41][N:42]([CH3:43])[CH:44]=[O:45].[Cl:1][c:2]1[c:3]([OH:22])[cH:4][c:5](-[n:9]2[c:10](=[O:21])[n:11]([CH3:20])[c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[c:6]([F:8])[cH:7]1.[K+:50].[K+:51].[OH2:52]>>[Cl:1][c:2]1[c:3]([O:22][c:29]2[n:28][c:27]([O:35][CH2:36][C:37](=[O:38])[O:39][CH3:40])[cH:26][c:25]([O:24][CH3:23])[n:30]2)[cH:4][c:5](-[n:9]2[c:10](=[O:21])[n:11]([CH3:20])[c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[c:6]([F:8])[cH:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 112677571-methyl-6-trifluoromethyl-3-(4-chloro-2-fluoro-5-hydroxyphenyl)-2,4(1H,3H)-pyrimidinedioneHCID 186191946-Methoxy-4-(methoxycarbonyl)methoxy-2-methylsulfonylpyrimidine

Product 1

HCID 186191952-{2-Chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}-6-methoxy-4-(methoxycarbonyl)methoxypyrimidine

Sources & evidence

ORD record
ord-2c0270d49e82437894132da25faff7a6
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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