Dimethylformamide → Ethyl 8'-amino-9',10'-difluoro-7'-oxospiro-[cyclobutane-1,3'(2'H)-[7H]pyrido[1,2,3-de][1,4]benzoxazine]-6'-carboxylate

HRID 953221Notes

Reaction equation

HRID 953221 reaction equation
[F:1][c:2]1[c:3]([F:27])[c:4]2[c:5]3[n:6]([cH:7][c:8]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[c:9](=[O:15])[c:10]3[c:11]1[N+:12]([O-:13])=[O:14])[C:21]1([CH2:22][CH2:23][CH2:24]1)[CH2:25][O:26]2.[H:28][H:29].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[F:1][c:2]1[c:3]([F:27])[c:4]2[c:5]3[n:6]([cH:7][c:8]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[c:9](=[O:15])[c:10]3[c:11]1[NH2:12])[C:21]1([CH2:22][CH2:23][CH2:24]1)[CH2:25][O:26]2

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 58134645ethyl 9',10'-difluoro-8'-nitro-7'-oxospiro[cyclobutane-1,3'(2'H)-[7H]pyrido[1,2,3-de][1,4]benzoxazine]-6'-carboxylateHCID 178418361HCID 178418361, compound

Product 1

HCID 58134855Ethyl 8'-amino-9',10'-difluoro-7'-oxospiro-[cyclobutane-1,3'(2'H)-[7H]pyrido[1,2,3-de][1,4]benzoxazine]-6'-carboxylate

Sources & evidence

ORD record
ord-0a2e4701727e4da681df72019cb6bf1c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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