Dichloromethane → Methyl 2-chloro-5-[(6-methyl-2,3-dihydro-1,4-oxathiine-5-carbonyl)amino]benzoate

HRID 953304Notes

Reaction equation

HRID 953304 reaction equation
[CH2:34]([Cl:35])[Cl:36].[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[CH3:5][C:6]1=[C:11]([C:12](=[O:13])[OH:14])[S:10][CH2:9][CH2:8][O:7]1.[NH2:15][c:16]1[cH:17][cH:18][c:19]([Cl:26])[c:20]([C:21](=[O:22])[O:23][CH3:24])[cH:25]1.[S:1]([Cl:2])([Cl:3])=[O:4]>>[CH3:5][C:6]1=[C:11]([C:12](=[O:14])[NH:15][c:16]2[cH:17][cH:18][c:19]([Cl:26])[c:20]([C:21](=[O:22])[O:23][CH3:24])[cH:25]2)[S:10][CH2:9][CH2:8][O:7]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 24386Thionyl ChlorideHCID 5399462-Methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acidHCID 5200412Methyl 5-Amino-2-chlorobenzoate

Product 1

HCID 465808Methyl 2-chloro-5-[(6-methyl-2,3-dihydro-1,4-oxathiine-5-carbonyl)amino]benzoate

Sources & evidence

ORD record
ord-3b08658aedeb49129d7bc11f258fdb52
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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