HRID953333

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID813

Potassium cation

K+

HCID962

Water

H2O

HCID8028

Tetrahydrofuran

C4H8O

HCID4574913

未命名化合物

HCID9994433

TERT-BUTYL 4-(HYDROXYMETHYL)-4-PHENYLPIPERIDINE-1-CARBOXYLATE

C17H25NO3

HCID53403739

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCC(COCc2cc(C(F)(F)F)cc(Cl)n2)(c2ccccc2)CC1

HCID57557581

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f5ca91f5ae714d1fab74d0269c6e1be2
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br:1][CH2:2][c:3]1[n:4][c:5]([Cl:13])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1.[CH3:35][C:36]([CH3:37])([O-:38])[CH3:39].[K+:40].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[OH2:46].[OH:14][CH2:15][C:16]1([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]1>>[CH2:2]([c:3]1[n:4][c:5]([Cl:13])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)[O:14][CH2:15][C:16]1([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]1