Trifluoroacetic acid → 2-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine
Reaction equation
[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:7]([n:8]1)[CH2:9][N:10]([C:12]([c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[CH2:11]2)([F:31])[F:32].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:7]([n:8]1)[CH2:9][NH:10][CH2:11]2)([F:31])[F:32]Participants
3
Sources & evidence
- ORD record
- ord-89a86dcfc9e1496ba114e519dfaf70a3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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