HRID953503

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID260

Hydrogen Bromide

BrH

HCID10661998

7-(benzyloxy)-4-chloro-6-methoxyquinazoline

C16H13ClN2O2

HCID21851223

未命名化合物

PRODUCTS

产物

HCID22923436

3-[1-(7-Benzyloxy-6-methoxy-4-quinazolinyl)-4-piperidinyl]-1,2,3,4-tetrahydro-1,6-dimethyl-2,4-dioxoquinazoline

C31H31N5O4

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-dbcaa6cf0c3949c8a3f46a92da4ef9ec
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[BrH:1].[CH2:22]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[O:29][c:30]1[c:31]([O:41][CH3:42])[cH:32][c:33]2[c:34]([Cl:40])[n:35][cH:36][n:37][c:38]2[cH:39]1.[CH3:2][n:3]1[c:4](=[O:21])[n:5]([CH:15]2[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]2)[c:6](=[O:14])[c:7]2[cH:8][c:9]([CH3:13])[cH:10][cH:11][c:12]12>>[CH3:2][n:3]1[c:4](=[O:21])[n:5]([CH:15]2[CH2:16][CH2:17][N:18]([c:34]3[c:33]4[cH:32][c:31]([O:41][CH3:42])[c:30]([O:29][CH2:22][c:23]5[cH:24][cH:25][cH:26][cH:27][cH:28]5)[cH:39][c:38]4[n:37][cH:36][n:35]3)[CH2:19][CH2:20]2)[c:6](=[O:14])[c:7]2[cH:8][c:9]([CH3:13])[cH:10][cH:11][c:12]12