Methylamine → 1-[5-methylaminomethyl-1-(3-methyl-butyl)-1H-benzoimidazol-2-ylmethyl]-3-isopropyl-1,3-dihydro-benzoimidazol-2-one

HRID 953538Notes

Reaction equation

HRID 953538 reaction equation
[CH3:35][NH2:36].[CH:1]([CH3:2])([CH3:3])[n:4]1[c:5](=[O:34])[n:6]([CH2:13][c:14]2[n:15][c:16]3[c:17]([n:18]2[CH2:19][CH2:20][CH:21]([CH3:22])[CH3:23])[cH:24][cH:25][c:26]([CH2:28][O:29][S:30]([CH3:31])(=[O:32])=[O:33])[cH:27]3)[c:7]2[c:8]1[cH:9][cH:10][cH:11][cH:12]2>>[CH:1]([CH3:2])([CH3:3])[n:4]1[c:5](=[O:34])[n:6]([CH2:13][c:14]2[n:15][c:16]3[c:17]([n:18]2[CH2:19][CH2:20][CH:21]([CH3:22])[CH3:23])[cH:24][cH:25][c:26]([CH2:28][NH:36][CH3:35])[cH:27]3)[c:7]2[c:8]1[cH:9][cH:10][cH:11][cH:12]2

Participants

3

Reactant 2

HCID 6329MethylamineHCID 20813972methanesulfonic acid 2-(3-isopropyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-1-(3-methyl-butyl)-1H-benzoimidazol-5-ylmethyl ester

Product 1

HCID 208139711-[5-methylaminomethyl-1-(3-methyl-butyl)-1H-benzoimidazol-2-ylmethyl]-3-isopropyl-1,3-dihydro-benzoimidazol-2-one

Sources & evidence

ORD record
ord-a82d501d4491400aad1d5eb1ed92e38a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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