Hydrochloric Acid → tert-butyl N-((4-(aminomethyl)cyclohexyl)methyl)carbamate

HRID 953717Notes

Reaction equation

HRID 953717 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH:9]1[CH2:10][CH2:11][CH:12]([CH2:15][NH:16][C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:13][CH2:14]1)=[O:24].[CH3:25][CH2:26][OH:27].[Cl:35][CH:36]([Cl:37])[Cl:38].[ClH:28].[O:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH:9]1[CH2:10][CH2:11][CH:12]([CH2:15][NH2:16])[CH2:13][CH2:14]1)=[O:24]

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 702EthanolHCID 6212ChloroformHCID 312751,4-DioxaneHCID 22668023[4-(Tert-butoxycarbonylamino-methyl)-cyclohexylmethyl]-carbamic acid tert-butyl ester

Product 1

HCID 2756046tert-butyl N-((4-(aminomethyl)cyclohexyl)methyl)carbamate

Sources & evidence

ORD record
ord-96f8426bb45642499aa745ce3586b1f3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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