Pyrrolidine → Methyl 2'-fluoro-5'-(methyloxy)-2-(1-pyrrolidinylmethyl)-1,1'-biphenyl-4-carboxylate
Reaction equation
[CH2:27]1[CH2:28][NH:29][CH2:30][CH2:31]1.[F:1][c:2]1[c:3](-[c:10]2[c:11]([CH2:20][N:21]3[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]3)[cH:12][c:13]([C:16](=[O:17])[O:18][CH3:19])[cH:14][cH:15]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1>>[F:1][c:2]1[c:3](-[c:10]2[c:11]([CH2:20][N:21]3[CH2:22][CH2:23][CH2:24][CH2:25]3)[cH:12][c:13]([C:16](=[O:17])[O:18][CH3:19])[cH:14][cH:15]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-85a356adfec34d6597573717f8b6d05a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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