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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 954048Generated: October 29, 2026

5-chloro-2-(trifluoromethyl)-1,8-Naphthyridine → 4-Fluoro-3'-(7-trifluoromethyl[1,8]naphthyridin-4-yl)biphenyl-2-carbonitrile

https://huagongshe.com/reaction/954048

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-chloro-2-(trifluoromethyl)-1,8-NaphthyridineHCID 22285276—
Reactant4-Fluoro-3'-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)biphenyl-2-carbonitrileHCID 22285336—
Product4-Fluoro-3'-(7-trifluoromethyl[1,8]naphthyridin-4-yl)biphenyl-2-carbonitrileHCID 10271874—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-0be7fa61ec934e989929793066ce2516
Source noteValidation data from https://doi.org/10.1039/C8SC04228D