Toluene → 6-(2-(2,5-Difluorophenyl)pyrrolidin-1-yl)-3-(6-fluoropyridin-2-yl)imidazo[1,2-b]pyridazine

HRID 954183Notes

Reaction equation

[Br:28][c:29]1[cH:30][n:31][c:32]2[n:33]1[n:34][c:35]([N:38]1[CH:39]([c:43]3[c:44]([F:50])[cH:45][cH:46][c:47]([F:49])[cH:48]3)[CH2:40][CH2:41][CH2:42]1)[cH:36][cH:37]2.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:51][c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1.[F:8][c:9]1[cH:10][cH:11][cH:12][c:13]([Sn:15]([CH2:16][CH2:17][CH2:18][CH3:19])([CH2:20][CH2:21][CH2:22][CH3:23])[CH2:24][CH2:25][CH2:26][CH3:27])[n:14]1>>[F:8][c:9]1[cH:10][cH:11][cH:12][c:13](-[c:29]2[cH:30][n:31][c:32]3[n:33]2[n:34][c:35]([N:38]2[CH:39]([c:43]4[c:44]([F:50])[cH:45][cH:46][c:47]([F:49])[cH:48]4)[CH2:40][CH2:41][CH2:42]2)[cH:36][cH:37]3)[n:14]1