Dimethylformamide → diethyl 3-(N-ethoxycarbonyl-N-ethoxycarbonyloxyamino)-2-hydroxypropylphosphonate

HRID 954198Notes

Reaction equation

HRID 954198 reaction equation
[CH2:37]([CH3:38])[O:39][C:40](=[O:41])[O:42][NH:43][C:44]([O:45][CH2:46][CH3:47])=[O:48].[CH3:24][Si:25]([CH:26]([Si:27]([CH3:28])([CH3:29])[CH3:30])[C:31]([NH2:32])=[O:33])([CH3:34])[CH3:35].[CH3:49][N:50]([CH3:51])[CH:52]=[O:53].[K:36].[OH:1][CH:2]([CH2:3][P:4]([O:5][CH2:6][CH3:7])([O:8][CH2:9][CH3:10])=[O:11])[CH2:12][O:13][S:14]([c:15]1[cH:16][cH:17][c:18]([CH3:19])[cH:20][cH:21]1)(=[O:22])=[O:23]>>[OH:1][CH:2]([CH2:3][P:4]([O:5][CH2:6][CH3:7])([O:8][CH2:9][CH3:10])=[O:11])[CH2:12][N:43]([O:42][C:40]([O:39][CH2:37][CH3:38])=[O:41])[C:44]([O:45][CH2:46][CH3:47])=[O:48]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 5462222PotassiumHCID 11446651Ethyl EthoxycarbonyloxycarbamateHCID 11708267BistrimethylsilylacetamidHCID 20337231(3-Diethoxyphosphoryl-2-hydroxypropyl) 4-methylbenzenesulfonate

Product 1

HCID 20337198diethyl 3-(N-ethoxycarbonyl-N-ethoxycarbonyloxyamino)-2-hydroxypropylphosphonate

Sources & evidence

ORD record
ord-33d1e009729341c48bd1a0b8346280cb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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