Tetrahydrofuran → 5-Bromo-3,4-difluoro-2-((2-fluorophenyl)amino)benzoic acid
Reaction equation
[Br:9][c:10]1[c:11]([F:21])[c:12]([F:20])[c:13]([F:19])[c:14]([C:15](=[O:16])[OH:17])[cH:18]1.[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[NH2:1][c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[F:8]>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][c:7]1[F:8])[c:13]1[c:12]([F:20])[c:11]([F:21])[c:10]([Br:9])[cH:18][c:14]1[C:15](=[O:16])[OH:17]Participants
4
Sources & evidence
- ORD record
- ord-b0528a34b5044ddbbbb11d4f673e28bc
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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