Dimethylformamide → 2-(2-Fluoro-phenyl)-4-pyrrolo[3,2-c]pyridin-1-yl-quinazoline

HRID 954241Notes

Reaction equation

HRID 954241 reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[CH3:34][N:35]([CH3:36])[CH:37]=[O:38].[Cl:1][c:2]1[n:3][c:4](-[c:12]2[c:13]([F:18])[cH:14][cH:15][cH:16][cH:17]2)[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[Cs+:32].[Cs+:33].[nH:19]1[cH:20][cH:21][c:22]2[cH:23][n:24][cH:25][cH:26][c:27]12>>[c:2]1(-[n:19]2[cH:20][cH:21][c:22]3[cH:23][n:24][cH:25][cH:26][c:27]23)[n:3][c:4](-[c:12]2[c:13]([F:18])[cH:14][cH:15][cH:16][cH:17]2)[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 92205-AzaindoleHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 47382154-Chloro-2-(2-fluoro-phenyl)-quinazoline

Product 1

HCID 184406432-(2-Fluoro-phenyl)-4-pyrrolo[3,2-c]pyridin-1-yl-quinazoline

Sources & evidence

ORD record
ord-a5c8129c3a6c4579a36daa4d611fd36a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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