Ammonium → Tert-butyl 2-((pyridin-3-yloxy)methyl)piperazine-1-carboxylate

HRID 954260Notes

Reaction equation

HRID 954260 reaction equation
[CH3:36][CH2:37][OH:38].[CH3:39][CH2:40][O:41][C:42]([CH3:43])=[O:44].[CH:32]([O-:33])=[O:34].[NH4+:35].[OH-:45].[OH-:47].[Pd+2:46].[n:1]1[cH:2][c:3]([O:7][CH2:8][CH:9]2[N:10]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:11][CH2:12][N:13]([C:15]([O:16][CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)=[O:24])[CH2:14]2)[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3]([O:7][CH2:8][CH:9]2[N:10]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:11][CH2:12][NH:13][CH2:14]2)[cH:4][cH:5][cH:6]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 283FormateHCID 702EthanolHCID 961Hydroxide2×HCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 596716061-Tert-butyl 4-benzyl 2-((pyridin-3-yloxy)methyl)piperazine-1,4-dicarboxylate

Product 1

HCID 59671473Tert-butyl 2-((pyridin-3-yloxy)methyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-6396891d76f0458f9907494a16001167
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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