Dimethyl Sulfoxide → 2-(4-Boc-Aminopiperidino)pyridine

HRID 954280Notes

Reaction equation

HRID 954280 reaction equation
[CH3:22][CH2:23][O:24][C:25]([CH3:26])=[O:27].[CH3:28][S:29]([CH3:30])=[O:31].[Cl:1][c:2]1[cH:3][cH:4][cH:5][cH:6][n:7]1.[NH:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:12][CH2:13]1>>[c:2]1([N:8]2[CH2:9][CH2:10][CH:11]([NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:12][CH2:13]2)[cH:3][cH:4][cH:5][cH:6][n:7]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 79772-ChloropyridineHCID 8857Ethyl AcetateHCID 7238334-(N-Boc-amino)piperidine

Product 1

HCID 537924442-(4-Boc-Aminopiperidino)pyridine

Sources & evidence

ORD record
ord-8e7b5fc7d74846ff8f928cb70f6c7ce8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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