Dichloromethane → 4-(3-Imidazol-1-yl-phenyl)-8-pyrrol-1-yl-1,3-dihydro-benzo[b][1,4]diazepin-2-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:19][C:20]([CH2:21][C:22](=[O:5])[c:24]2[cH:25][c:26](-[n:30]3[cH:31][n:32][cH:33][cH:34]3)[cH:27][cH:28][cH:29]2)=[O:35])[cH:10][c:11](-[n:14]2[cH:15][cH:16][cH:17][cH:18]2)[cH:12][cH:13]1)([CH3:6])([CH3:23])[CH3:36].[Cl:44][CH2:45][Cl:46].[F:37][C:38]([F:39])([F:40])[C:41]([OH:42])=[O:43]>>[N:7]1=[C:22]([c:24]2[cH:25][c:26](-[n:30]3[cH:31][n:32][cH:33][cH:34]3)[cH:27][cH:28][cH:29]2)[CH2:21][C:20](=[O:35])[NH:19][c:9]2[c:8]1[cH:13][cH:12][c:11](-[n:14]1[cH:15][cH:16][cH:17][cH:18]1)[cH:10]2Participants
4
Sources & evidence
- ORD record
- ord-37dde48e140a4a0c8193099ed56c643a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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