Potassium Cation → Tert-butyl 4-(cyclopropanecarbonyl)piperazine-1-carboxylate

HRID 954296Notes

Reaction equation

HRID 954296 reaction equation
[C:14](=[O:15])([O-:16])[O-:17].[CH:20]1([C:23](=[O:24])[Cl:25])[CH2:21][CH2:22]1.[Cl:26][CH2:27][Cl:28].[K+:18].[K+:19].[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][N:4]([C:23]([CH:20]2[CH2:21][CH2:22]2)=[O:24])[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6344DichloromethaneHCID 19660Carbonate IonHCID 77637Cyclopropanecarbonyl chlorideHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 968936Tert-butyl 4-(cyclopropanecarbonyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-127b959c5c9f4f68b2e86b228fcc8a09
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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