Isopropanol → 5-Bromo-3-(4-(1-ethyl-3-oxopiperazin-2-yl)phenylamino]-1-methylpyrazin-2(1H)-one

HRID 95437Notes

Reaction equation

HRID 95437 reaction equation
[Br:17][c:18]1[c:19](=[O:26])[n:20]([CH3:25])[cH:21][c:22]([Br:24])[n:23]1.[CH:27]([OH:28])([CH3:29])[CH3:30].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[C:9](=[O:16])[NH:10][CH2:11][CH2:12][N:13]2[CH2:14][CH3:15])[cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH:8]2[C:9](=[O:16])[NH:10][CH2:11][CH2:12][N:13]2[CH2:14][CH3:15])[cH:6][cH:7]1)[c:18]1[c:19](=[O:26])[n:20]([CH3:25])[cH:21][c:22]([Br:24])[n:23]1

Participants

4

Reactant 3

HCID 3776IsopropanolHCID 130629693,5-Dibromo-1-methyl-1H-pyrazin-2-oneHCID 576251673-(4-Aminophenyl)-4-ethylpiperazin-2-one

Product 1

HCID 576251865-Bromo-3-(4-(1-ethyl-3-oxopiperazin-2-yl)phenylamino]-1-methylpyrazin-2(1H)-one

Sources & evidence

ORD record
ord-22ec86f8a3a7401e88f04ad5bef6606e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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