p-Toluenesulfonic acid → N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Reaction equation
[CH2:36]([CH3:37])[O:38][c:39]1[c:40]([NH2:41])[cH:42][cH:43][c:44]([N:46]2[CH2:47][CH2:48][CH:49]([N:52]3[CH2:53][CH2:54][N:55]([S:58](=[O:59])(=[O:60])[CH3:61])[CH2:56][CH2:57]3)[CH2:50][CH2:51]2)[cH:45]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH3:35])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1.[c:62]1([CH3:63])[cH:64][cH:65][c:66]([S:67]([OH:68])(=[O:69])=[O:70])[cH:71][cH:72]1>>[c:2]1([NH:41][c:40]2[c:39]([O:38][CH2:36][CH3:37])[cH:45][c:44]([N:46]3[CH2:47][CH2:48][CH:49]([N:52]4[CH2:53][CH2:54][N:55]([S:58](=[O:59])(=[O:60])[CH3:61])[CH2:56][CH2:57]4)[CH2:50][CH2:51]3)[cH:43][cH:42]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH3:35])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-2db5d3486cad4e8191c9742e3142c364
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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