Ethanol → 5-iodo-N-(6-methoxypyridin-3-yl)-2-(piperidin-1-yl)pyrimidin-4-amine
Reaction equation
[CH2:18]1[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1.[CH3:24][CH2:25][OH:26].[Cl:1][c:2]1[n:3][cH:4][c:5]([I:17])[c:6]([NH:8][c:9]2[cH:10][n:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[n:7]1.[OH2:27]>>[c:2]1([N:21]2[CH2:20][CH2:19][CH2:18][CH2:23][CH2:22]2)[n:3][cH:4][c:5]([I:17])[c:6]([NH:8][c:9]2[cH:10][n:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[n:7]1Participants
5
Sources & evidence
- ORD record
- ord-f0965cb525e540ecade5a258895af0a4
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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