Hydrochloric Acid → 2,2,2-trichloroethyl N-[[3-[4-(3-aminopyrrolidin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-(1,2-oxazol-3-yl)carbamate

HRID 954829Notes

Reaction equation

HRID 954829 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][CH:9]1[CH2:10][N:11]([c:14]2[c:15]([F:41])[cH:16][c:17]([N:20]3[C:21](=[O:40])[O:22][CH:23]([CH2:25][N:26]([C:27](=[O:28])[O:29][CH2:30][C:31]([Cl:32])([Cl:33])[Cl:34])[c:35]4[n:36][o:37][cH:38][cH:39]4)[CH2:24]3)[cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:46][CH2:47][OH:48].[Cl:43][CH2:44][Cl:45].[ClH:42]>>[NH2:8][CH:9]1[CH2:10][N:11]([c:14]2[c:15]([F:41])[cH:16][c:17]([N:20]3[C:21](=[O:40])[O:22][CH:23]([CH2:25][N:26]([C:27](=[O:28])[O:29][CH2:30][C:31]([Cl:32])([Cl:33])[Cl:34])[c:35]4[n:36][o:37][cH:38][cH:39]4)[CH2:24]3)[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 6344DichloromethaneHCID 178452834HCID 178452834, compound

Product 1

HCID 1785078732,2,2-trichloroethyl N-[[3-[4-(3-aminopyrrolidin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]-N-(1,2-oxazol-3-yl)carbamate

Sources & evidence

ORD record
ord-a00fc3fbb5ea468b9354dcba41ca3a68
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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