HRID95483

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID962

Water

H2O

HCID11776

Triphenylphosphine

C18H15P

4 次

HCID23938

Palladium

HCID31275

1,4-Dioxane

C4H8O2

HCID2783171

2-Bromo-5-fluoropyridine

C5H3BrFN

HCID86638518

4-Bromo-α,α-difluoro-N-methoxy-N-methylbenzeneacetamide

C10H10BrF2NO2

PRODUCTS

生成物

结构：CON(C)C(=O)C(F)(F)c1ccc(-c2ccc(F)cn2)cc1

HCID86638517

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4f403d261c0b49feb5552bb105f58214
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (2/10)

反应 SMILES

[Br:17][c:18]1[n:19][cH:20][c:21]([F:24])[cH:22][cH:23]1.[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]([C:9](=[O:10])[N:11]([CH3:12])[O:13][CH3:14])([F:15])[F:16])[cH:6][cH:7]1.[CH2:25]1[O:26][CH2:27][CH2:28][O:29][CH2:30]1.[OH2:31].[Pd:108].[c:32]1([P:33]([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[cH:46][cH:47][cH:48][cH:49][cH:50]1.[c:51]1([P:52]([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[cH:65][cH:66][cH:67][cH:68][cH:69]1.[c:70]1([P:71]([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[cH:84][cH:85][cH:86][cH:87][cH:88]1.[c:89]1([P:90]([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)[cH:103][cH:104][cH:105][cH:106][cH:107]1>>[c:2]1(-[c:18]2[n:19][cH:20][c:21]([F:24])[cH:22][cH:23]2)[cH:3][cH:4][c:5]([C:8]([C:9](=[O:10])[N:11]([CH3:12])[O:13][CH3:14])([F:15])[F:16])[cH:6][cH:7]1