Tetrahydrofuran → Methyl 3-bromo-5-(dipropylcarbamoyl)benzoate

HRID 954837Notes

Reaction equation

HRID 954837 reaction equation
[Br:13][c:14]1[cH:15][c:16]([C:17](=[O:18])[OH:19])[cH:20][c:21]([C:23](=[O:24])[O:25][CH3:26])[cH:22]1.[C:1]([c:2]1[nH:3][cH:4][cH:5][n:6]1)([c:7]1[nH:8][cH:9][cH:10][n:11]1)=[O:12].[CH2:27]([CH2:28][CH3:29])[NH:30][CH2:31][CH2:32][CH3:33].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1>>[Br:13][c:14]1[cH:15][c:16]([C:17](=[O:19])[N:30]([CH2:27][CH2:28][CH3:29])[CH2:31][CH2:32][CH3:33])[cH:20][c:21]([C:23](=[O:24])[O:25][CH3:26])[cH:22]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8902DipropylamineHCID 5250894Bis-(1H-imidazol-2-YL)-methanoneHCID 225936413-Bromo-5-(methoxycarbonyl)benzoic acid

Product 1

HCID 21939662Methyl 3-bromo-5-(dipropylcarbamoyl)benzoate

Sources & evidence

ORD record
ord-7bd45d5ce3974f1fa4f04b1605185a29
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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