Acetaldehyde → 6-Chloro-α-methyl-5-(phenylmethoxy)-2-pyridinemethanol

HRID 955254Notes

Reaction equation

HRID 955254 reaction equation
[CH2:17]([Li:18])[CH2:19][CH2:20][CH3:21].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH:22]([CH3:23])=[O:24].[Cl:1][c:2]1[n:3][c:4]([I:16])[cH:5][cH:6][c:7]1[O:8][CH2:9][c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1>>[Cl:1][c:2]1[n:3][c:4]([CH:22]([CH3:23])[OH:24])[cH:5][cH:6][c:7]1[O:8][CH2:9][c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1

Participants

5

Reactant 4

HCID 177AcetaldehydeHCID 8028TetrahydrofuranHCID 18799610HCID 18799610, compoundHCID 178418339Butyllithium

Product 1

HCID 187996156-Chloro-α-methyl-5-(phenylmethoxy)-2-pyridinemethanol

Sources & evidence

ORD record
ord-b7a7b45d6e3f458e80b2890c99c7ce2c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…