Hydrochloric Acid → 5-Pyrrolidin-1-yl-2,3-dihydro-1H-isoindole

HRID 955261Notes

Reaction equation

HRID 955261 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[cH:14][c:15]2[CH2:16]1)([CH3:5])([CH3:6])[CH3:7].[ClH:22]>>[NH:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[cH:14][c:15]2[CH2:16]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 577534845-Pyrrolidin-1-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

Product 1

HCID 577533975-Pyrrolidin-1-yl-2,3-dihydro-1H-isoindole

Sources & evidence

ORD record
ord-9bfaa35c175742b79ff97184f6ab8ae2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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