Tetrahydrofuran → 2-Phenoxymethyl-1-(4-trifluoromethoxy-benzyl)-1H-benzoimidazole-5-carboxylic acid (2,2-dimethyl propyl)-amide
Reaction equation
[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:33][C:34]([CH2:35][NH2:36])([CH3:37])[CH3:38].[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH2:8][c:9]1[n:10][c:11]2[c:12]([n:13]1[CH2:14][c:15]1[cH:16][cH:17][c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]1)[cH:26][cH:27][c:28]([C:30](=[O:31])[OH:32])[cH:29]2>>[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH2:8][c:9]1[n:10][c:11]2[c:12]([n:13]1[CH2:14][c:15]1[cH:16][cH:17][c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]1)[cH:26][cH:27][c:28]([C:30](=[O:31])[NH:36][CH2:35][C:34]([CH3:33])([CH3:37])[CH3:38])[cH:29]2Participants
4
Sources & evidence
- ORD record
- ord-326c25430ffd4fc4a4e6b9205e956b01
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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