Dimethylformamide → 2,4-Diamino-5-(2,4-dichlorophenyl)-6-cyanomethyl-pyrimidine
Reaction equation
[NH2:1][c:2]1[n:3][c:4]([CH2:17][Br:18])[c:5](-[c:9]2[c:10]([Cl:16])[cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[c:6]([NH2:8])[n:7]1.[Na:19][C:20]#[N:21].[O:22]=[CH:23][N:24]([CH3:25])[CH3:26]>>[NH2:1][c:2]1[n:3][c:4]([CH2:17][C:20]#[N:21])[c:5](-[c:9]2[c:10]([Cl:16])[cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[c:6]([NH2:8])[n:7]1Participants
4
Sources & evidence
- ORD record
- ord-cd10d0b224054c71aebcb10a123dd09d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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