Isoamyl Alcohol → 4-Amino-2-(pyrrolidin-1-yl)-6-(2-chlorophenyl)-5,6,7,8-tetrahydroquinazoline
Reaction equation
[CH2:22]1[CH2:23][CH2:24][NH:25][CH2:26]1.[CH2:27]([OH:28])[CH2:29][CH:30]([CH3:31])[CH3:32].[NH2:1][c:2]1[n:3][c:4]([S:19]([CH3:20])=[O:21])[n:5][c:6]2[c:11]1[CH2:10][CH:9]([c:12]1[c:13]([Cl:18])[cH:14][cH:15][cH:16][cH:17]1)[CH2:8][CH2:7]2>>[NH2:1][c:2]1[n:3][c:4]([N:25]2[CH2:24][CH2:23][CH2:22][CH2:26]2)[n:5][c:6]2[c:11]1[CH2:10][CH:9]([c:12]1[c:13]([Cl:18])[cH:14][cH:15][cH:16][cH:17]1)[CH2:8][CH2:7]2Participants
4
Sources & evidence
- ORD record
- ord-93e6c3ffa4974e08b8b432ae64fddc36
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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