Sodium ion → 3-(1-Methoxy-1-Phenylethyl)-4-Phenyl-8-(Trifluoromethyl)Quinoline

HRID 955712Notes

Reaction equation

HRID 955712 reaction equation
[H-:31].[I:32][CH3:33].[Na+:30].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38].[c:1]1([C:7]([CH3:8])([OH:9])[c:10]2[cH:11][n:12][c:13]3[c:14]([C:26]([F:27])([F:28])[F:29])[cH:15][cH:16][cH:17][c:18]3[c:19]2-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]([CH3:8])([O:9][CH3:33])[c:10]2[cH:11][n:12][c:13]3[c:14]([C:26]([F:27])([F:28])[F:29])[cH:15][cH:16][cH:17][c:18]3[c:19]2-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 166653HydrideHCID 113498961-Phenyl-1-[4-phenyl-8-(trifluoromethyl)quinolin-3-yl]ethanol

Product 1

HCID 669131893-(1-Methoxy-1-Phenylethyl)-4-Phenyl-8-(Trifluoromethyl)Quinoline

Sources & evidence

ORD record
ord-0d3a5a5c521b4c0889fa0653e2a718a2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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