Potassium Cation → ethyl 3-[3-phenyl-1-[4-(5-phenyl-3-pyridylmethoxy)benzyl]-1H-pyrazol-4-yl]propionate

HRID 955811Notes

Reaction equation

HRID 955811 reaction equation
[C:41](=[O:42])([O-:43])[O-:44].[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[Cl:27][CH2:28][c:29]1[cH:30][n:31][cH:32][c:33](-[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:34]1.[K+:45].[K+:46].[OH2:52].[OH:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][n:7]2[n:8][c:9](-[c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[c:10]([CH2:12][CH2:13][C:14](=[O:15])[O:16][CH2:17][CH3:18])[cH:11]2)[cH:25][cH:26]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([CH2:6][n:7]2[n:8][c:9](-[c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[c:10]([CH2:12][CH2:13][C:14](=[O:15])[O:16][CH2:17][CH3:18])[cH:11]2)[cH:25][cH:26]1)[CH2:28][c:29]1[cH:30][n:31][cH:32][c:33](-[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:34]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 110849253-(Chloromethyl)-5-phenylpyridineHCID 23024792ethyl 3-[1-(4-hydroxybenzyl)-3-phenyl-1H-pyrazol-4-yl]propionate

Product 1

HCID 23025101ethyl 3-[3-phenyl-1-[4-(5-phenyl-3-pyridylmethoxy)benzyl]-1H-pyrazol-4-yl]propionate

Sources & evidence

ORD record
ord-55e6d9b4d6594f8383eaae9dbc2b76d8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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