Sodium ion → Methyl 7-[4-(4-morpholinyl)phenyl]-1-benzothiophene-2-carboxylate

HRID 955814Notes

Reaction equation

HRID 955814 reaction equation
[Br:7][c:8]1[cH:9][cH:10][cH:11][c:12]2[cH:13][c:14]([C:17](=[O:18])[O:19][CH3:20])[s:15][c:16]12.[Na+:1].[Na+:2].[O-:3][C:4](=[O:5])[O-:6].[O:21]1[CH2:22][CH2:23][N:24]([c:27]2[cH:28][cH:29][c:30]([B:33]([OH:34])[OH:35])[cH:31][cH:32]2)[CH2:25][CH2:26]1.[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[c:8]1(-[c:30]2[cH:29][cH:28][c:27]([N:24]3[CH2:23][CH2:22][O:21][CH2:26][CH2:25]3)[cH:32][cH:31]2)[cH:9][cH:10][cH:11][c:12]2[cH:13][c:14]([C:17](=[O:18])[O:19][CH3:20])[s:15][c:16]12

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 2795359(4-(Morpholin-4-yl)phenyl)boronic acidHCID 18526159Methyl 7-bromobenzo[b]thiophene-2-carboxylate

Product 1

HCID 58485644Methyl 7-[4-(4-morpholinyl)phenyl]-1-benzothiophene-2-carboxylate

Sources & evidence

ORD record
ord-ee206b312524454f85c123c82d9f5451
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…