Ammonia → 5-Iodo-2-pyrrolidin-1-ylmethyl-benzoxazole

HRID 955860Notes

Reaction equation

HRID 955860 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7][c:8]([CH2:10][N:11]3[CH2:12][CH2:13][CH2:14][CH2:15]3)[o:9]2)[cH:16]1.[CH2:29]1[O:30][CH2:31][CH2:32][O:33][CH2:34]1.[CH3:19][NH:20][CH2:21][CH2:22][NH:23][CH3:24].[Cu:27][I:28].[I-:17].[NH3:25].[Na+:18].[OH2:26]>>[c:2]1([I:17])[cH:3][cH:4][c:5]2[c:6]([n:7][c:8]([CH2:10][N:11]3[CH2:12][CH2:13][CH2:14][CH2:15]3)[o:9]2)[cH:16]1

Participants

9

Reactant 8

HCID 222AmmoniaHCID 923Sodium ionHCID 962WaterHCID 8070N,N'-DimethylethylenediamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 30165Iodide IonHCID 312751,4-DioxaneHCID 673655735-Bromo-2-pyrrolidin-1-ylmethyl-benzoxazole

Product 1

HCID 690723805-Iodo-2-pyrrolidin-1-ylmethyl-benzoxazole

Sources & evidence

ORD record
ord-c4d8a9f394654e5e9e6521c1de529a23
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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