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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 955863Generated: October 31, 2026

Hydrochloric Acid → 1-Chloro-2-(difluoromethoxy)-3-fluorobenzene

https://huagongshe.com/reaction/955863

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantDiethyl EtherHCID 3283—
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
Reactant2-Chloro-6-fluorophenolHCID 2773710—
Reactant2-Chloro-2,2-difluoroacetateHCID 3763046—
Product1-Chloro-2-(difluoromethoxy)-3-fluorobenzeneHCID 59432130—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-fa5a27243b594e05b163ca5d498340f0
Source noteValidation data from https://doi.org/10.1039/C8SC04228D