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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 955880Generated: October 25, 2026

2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridine → 2-Chloro-4-[1-(2,2-difluoro-ethyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine

https://huagongshe.com/reaction/955880

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridineHCID 21985391—
Reactant1H-Imidazole, 1-(2,2-difluoroethyl)-4-iodo-2-methyl-HCID 21985393—
Product2-Chloro-4-[1-(2,2-difluoro-ethyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridineHCID 11289031—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-e6ed28f47ed24e29aa379acc92be5873
Source noteValidation data from https://doi.org/10.1039/C8SC04228D