1-(4-Fluorophenyl)piperazine → 1-(7-Ethoxy-2,2,4,6-tetramethyl-2,3-dihydro-1-benzofuran-5-yl)-4-(4-fluorophenyl)piperazine
Reaction equation
[Br:1][c:2]1[c:3]([CH3:17])[c:4]([O:14][CH2:15][CH3:16])[c:5]2[c:6]([c:12]1[CH3:13])[CH2:7][C:8]([CH3:10])([CH3:11])[O:9]2.[F:18][c:19]1[cH:20][cH:21][c:22]([N:25]2[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]2)[cH:23][cH:24]1>>[c:2]1([N:28]2[CH2:27][CH2:26][N:25]([c:22]3[cH:21][cH:20][c:19]([F:18])[cH:24][cH:23]3)[CH2:30][CH2:29]2)[c:3]([CH3:17])[c:4]([O:14][CH2:15][CH3:16])[c:5]2[c:6]([c:12]1[CH3:13])[CH2:7][C:8]([CH3:10])([CH3:11])[O:9]2Participants
3
Sources & evidence
- ORD record
- ord-9e3e907aef144564968fd33e90501a19
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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